Full listing on Google Scholar

Publications

Beitnere U, Vilanova-Cuevas B, Christian SG, Taylor C, Berg EL, Copping NA, Dindot SV, Silverman JL, Gareau MG, Segal DJ. Unique Features of the Gut Microbiome Characterized in Animal Models of Angelman Syndrome. mSystems. 2023 Feb 23;8(1):e0060822. doi: 10.1128/msystems.00608-22. Epub 2023 Jan 4. PMID: 36598241

Hennessey C, Keogh CE, Barboza M, Brust-Mascher I, Knotts TA, Sladek JA, Pusceddu MM, Stokes P, Rabasa G, Honeycutt M, Walsh O, Nichols R, Reardon C, Gareau MG. Neonatal Enteropathogenic Escherichia coli Infection Disrupts Microbiota-Gut-Brain Axis Signaling. Infect Immun. 2021 Aug 16;89(9):e0005921. doi: 10.1128/IAI.00059-21. Epub 2021 Aug 16. PMID: 33820817

Keogh CE, Kim DHJ, Pusceddu MM, Knotts TA, Rabasa G, Sladek JA, Hsieh MT, Honeycutt M, Brust-Mascher I, Barboza M, Gareau MG. Myelin as a regulator of development of the microbiota-gut-brain axis. Brain Behav Immun. 2021 Jan;91:437-450. doi: 10.1016/j.bbi.2020.11.001. Epub 2020 Nov 4. PMID: 33157256

Salvo E, Stokes P, Keogh CE, Brust-Mascher I, Hennessey C, Knotts TA, Sladek JA, Rude KM, Swedek M, Rabasa G, Gareau MG. A murine model of pediatric inflammatory bowel disease causes microbiota-gut-brain axis deficits in adulthood. Am J Physiol Gastrointest Liver Physiol. 2020 Sep 1;319(3):G361-G374. doi: 10.1152/ajpgi.00177.2020. Epub 2020 Jul 29. PMID: 32726162

Ferdek P, Gareau MG, Gonzalez J, Wilson C. Shaping the future of physiology. J Physiol. 2020 Jul;598(13):2511-2512. doi: 10.1113/JP280152. PMID: 32608047

Heskett CW, Teafatiller T, Hennessey C, Gareau MG, Marchant JS, Said HM, Subramanian VS. Enteropathogenic Escherichia coli Infection Inhibits Intestinal Ascorbic Acid Uptake via Dysregulation of Its Transporter Expression. Dig Dis Sci. 2020 Jun 17. doi: 10.1007/s10620-020-06389-x. Online ahead of print. PMID: 32556816

Hadian Y, Fregoso D, Nguyen C, Bagood MD, Dahle SE, Gareau MG, Isseroff RR. Microbiome-skin-brain axis: A novel paradigm for cutaneous wounds. Wound Repair Regen. 2020 May;28(3):282-292. doi: 10.1111/wrr.12800. Epub 2020 Mar 13. PMID: 32034844

Ramirez VT, Sladek J, Godinez DR, Rude KM, Chicco P, Murray K, Brust-Mascher I, Gareau MG, Reardon C. Sensory Nociceptive Neurons Contribute to Host Protection During Enteric Infection With Citrobacter rodentium. J Infect Dis. 2020 Jun 11;221(12):1978-1988. doi: 10.1093/infdis/jiaa014. PMID: 31960920

Pusceddu MM, Barboza M, Keogh CE, Schneider M, Stokes P, Sladek JA, Kim HJD, Torres-Fuentes C, Goldfild LR, Gillis SE, Brust-Mascher I, Rabasa G, Wong KA, Lebrilla C, Byndloss MX, Maisonneuve C, Bäumler AJ, Philpott DJ, Ferrero RL, Barrett KE, Reardon C, Gareau MG. Nod-like receptors are critical for gut-brain axis signalling in mice. J Physiol. 2019 Dec;597(24):5777-5797. doi: 10.1113/JP278640. Epub 2019 Nov 27. PMID: 31652348

Rude KM, Keogh CE, Gareau MG. The role of the gut microbiome in mediating neurotoxic outcomes to PCB exposure. Neurotoxicology. 2019 Aug 24;75:30-40. doi: 10.1016/j.neuro.2019.08.010. [Epub ahead of print] PMID: 31454514

Rude KM, Pusceddu MM, Keogh CE, Sladek JA, Rabasa G, Miller EN, Sethi S, Keil KP, Pessah IN, Lein PJ, Gareau MG. Developmental exposure to polychlorinated biphenyls (PCBs) in the maternal diet causes host-microbe defects in weanling offspring mice. Environ Pollut. 2019 Oct;253:708-721. doi: 10.1016/j.envpol.2019.07.066. Epub 2019 Jul 14. PMID: 31336350

Pusceddu MM, Stokes PJ, Wong A, Gareau MG, Genetos DC. Sexually Dimorphic Influence of Neonatal Antibiotics on Bone. J Orthop Res. 2019 Oct;37(10):2122-2129. doi: 10.1002/jor.24396. Epub 2019 Jul 26. PMID: 31228216

Nguyen CM, Tartar DM, Bagood MD, So M, Nguyen AV, Gallegos A, Fregoso D, Serrano J, Nguyen D, Degovics D, Adams A, Harouni B, Fuentes JJ, Gareau MG, Crawford RW, Soulika AM, Isseroff RR. Topical Fluoxetine as a Novel Therapeutic That Improves Wound Healing in Diabetic Mice. Diabetes. 2019 Jul;68(7):1499-1507. doi: 10.2337/db18-1146. Epub 2019 May 2. PMID: 31048368

Ramirez VT, Godinez DR, Brust-Mascher I, Nonnecke EB, Castillo PA, Gardner MB, Tu D, Sladek JA, Miller EN, Lebrilla CB, Bevins CL, Gareau MG, Reardon C. T-cell derived acetylcholine aids host defenses during enteric bacterial infection with Citrobacter rodentium. PLoS Pathog. 2019 Apr 11;15(4):e1007719. doi: 10.1371/journal.ppat.1007719. eCollection 2019 Apr. PMID: 30973939

Pusceddu MM, Gareau MG. Visceral pain: gut microbiota, a new hope? J Biomed Sci. 2018 Oct 11;25(1):73. doi: 10.1186/s12929-018-0476-7. Review. PMID: 30309367

Alisson-Silva F, Liu JZ, Diaz SL, Deng L, Gareau MG, Marchelletta R, Chen X, Nizet V, Varki N, Barrett KE, Varki A. Human evolutionary loss of epithelial Neu5Gc expression and species-specific susceptibility to cholera. PLoS Pathog. 2018 Jun 18;14(6):e1007133. doi: 10.1371/journal.ppat.1007133. eCollection 2018 Jun. PMID: 29912959

Pusceddu MM, Murray K, Gareau MG. Targeting the Microbiota, from Irritable Bowel Syndrome to Mood Disorders: Focus on Probiotics and Prebiotics. Curr Pathobiol Rep. 2018 Mar;6(1):1-13. doi: 10.1007/s40139-018-0160-3. Epub 2018 Feb 12. PMID: 29785336

Heeney DD, Gareau MG, Marco ML. Intestinal Lactobacillus in health and disease, a driver or just along for the ride? Curr Opin Biotechnol. 2018 Feb;49:140-147. doi: 10.1016/j.copbio.2017.08.004. Epub 2017 Sep 1. Review. PubMed PMID: 28866243; PubMed Central PMCID: PMC5808898.

Murray K, Godinez DR, Brust-Mascher I, Miller EN, Gareau MG, Reardon C. Neuroanatomy of the spleen: Mapping the relationship between sympathetic neurons and lymphocytes. PLoS One. 2017 Jul 28;12(7):e0182416. doi:10.1371/journal.pone.0182416. eCollection 2017. PubMed PMID: 28753658; PubMed Central PMCID: PMC5533443.

Gareau MG. Cognitive Function and the Microbiome. Int Rev Neurobiol. 2016;131:227-246. doi: 10.1016/bs.irn.2016.08.001. Epub 2016 Sep 9. Review. PubMed PMID: 27793221.

Emge JR, Huynh K, Miller EN, Kaur M, Reardon C, Barrett KE, Gareau MG. Modulation of the microbiota-gut-brain axis by probiotics in a murine model of inflammatory bowel disease. Am J Physiol Gastrointest Liver Physiol. 2016 Jun 1;310(11):G989-98. doi: 10.1152/ajpgi.00086.2016. Epub 2016 Apr 7. PubMed PMID: 27056723.

Johnson AM, Costanzo A, Gareau MG, Armando AM, Quehenberger O, Jameson JM, Olefsky JM. High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. PLoS One. 2015 Apr 2;10(4):e0122195. doi: 10.1371/journal.pone.0122195. eCollection 2015. PubMed PMID: 25837594; PubMed Central PMCID: PMC4383570.

Marchelletta RR, Gareau MG, Okamoto S, Guiney DG, Barrett KE, Fierer J. Salmonella-induced Diarrhea Occurs in the Absence of IL-8 Receptor (CXCR2)-Dependent Neutrophilic Inflammation. J Infect Dis. 2015 Jul 1;212(1):128-36. doi: 10.1093/infdis/jiu829. Epub 2014 Dec 23. PubMed PMID: 25538271; PubMed Central PMCID: PMC4542593.

de Jong PR, Takahashi N, Peiris M, Bertin S, Lee J, Gareau MG, Paniagua A, Harris AR, Herdman DS, Corr M, Blackshaw LA, Raz E. TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP. Mucosal Immunol. 2015 May;8(3):491-504. doi: 10.1038/mi.2014.82. Epub 2014 Oct 1. PubMed PMID: 25269705; PubMed Central PMCID: PMC4382463.

Smith CJ, Emge JR, Berzins K, Lung L, Khamishon R, Shah P, Rodrigues DM, Sousa AJ, Reardon C, Sherman PM, Barrett KE, Gareau MG. Probiotics normalize the gut-brain-microbiota axis in immunodeficient mice. Am J Physiol Gastrointest Liver Physiol. 2014 Oct 15;307(8):G793-802. doi: 10.1152/ajpgi.00238.2014. Epub 2014 Sep 4. PubMed PMID: 25190473; PubMed Central PMCID: PMC4200314.

Gareau MG. Microbiota-gut-brain axis and cognitive function. Adv Exp Med Biol. 2014;817:357-71. doi: 10.1007/978-1-4939-0897-4_16. Review. PubMed PMID: 24997042.

Gareau MG, Barrett KE. Fluid and electrolyte secretion in the inflamed gut: novel targets for treatment of inflammation-induced diarrhea. Curr OpinPharmacol. 2013 Dec;13(6):895-9. doi: 10.1016/j.coph.2013.08.014. Epub 2013 Sep 17. Review. PubMed PMID: 24054811.

Marchelletta RR, Gareau MG, McCole DF, Okamoto S, Roel E, Klinkenberg R, Guiney DG, Fierer J, Barrett KE. Altered expression and localization of ion transporters contribute to diarrhea in mice with Salmonella-induced enteritis. Gastroenterology. 2013 Dec;145(6):1358-1368.e1-4. doi: 10.1053/j.gastro.2013.08.054. Epub 2013 Aug 31. PubMed PMID: 24001788; PubMed Central PMCID: PMC3899031.

Fattouh R, Guo CH, Lam GY, Gareau MG, Ngan BY, Glogauer M, Muise AM, Brumell JH. Rac2-deficiency leads to exacerbated and protracted colitis in response to Citrobacter rodentium infection. PLoS One. 2013 Apr 16;8(4):e61629. doi: 10.1371/journal.pone.0061629. Print 2013. PubMed PMID: 23613889; PubMed Central PMCID: PMC3628927.

McAllister CS, Lakhdari O, Pineton de Chambrun G, Gareau MG, Broquet A, Lee GH, Shenouda S, Eckmann L, Kagnoff MF. TLR3, TRIF, and caspase 8 determine double-stranded RNA-induced epithelial cell death and survival in vivo. J Immunol. 2013 Jan 1;190(1):418-27. doi: 10.4049/jimmunol.1202756. Epub 2012 Dec 3. PubMed PMID: 23209324; PubMed Central PMCID: PMC3551582.

Rodrigues DM, Sousa AJ, Hawley SP, Vong L, Gareau MG, Kumar SA, Johnson-Henry KC, Sherman PM. Matrix metalloproteinase 9 contributes to gut microbe homeostasis in a model of infectious colitis. BMC Microbiol. 2012 Jun 13;12:105. doi:
10.1186/1471-2180-12-105. PubMed PMID: 22694805; PubMed Central PMCID: PMC3676156.

Rodrigues DM, Sousa AJ, Johnson-Henry KC, Sherman PM, Gareau MG. Probiotics are effective for the prevention and treatment of Citrobacter rodentium-induced colitis in mice. J Infect Dis. 2012 Jul 1;206(1):99-109. doi: 10.1093/infdis/jis177. Epub 2012 Mar 19. PubMed PMID: 22430833.

Gareau MG. Diet and nerves: the impact of maternal feeding on newborn intestinal permeability. J Physiol. 2011 Sep 1;589(17):4091. doi: 10.1113/jphysiol.2011.215723. PubMed PMID: 21885444; PubMed Central PMCID: PMC3180567.

Reardon C, Lechmann M, Brüstle A, Gareau MG, Shuman N, Philpott D, Ziegler SF, Mak TW. Thymic stromal lymphopoetin-induced expression of the endogenous inhibitory enzyme SLPI mediates recovery from colonic inflammation. Immunity. 2011 Aug 26;35(2):223-35. doi: 10.1016/j.immuni.2011.05.015. Epub 2011 Aug 4. PubMed PMID: 21820333; PubMed Central PMCID: PMC3169330.

Gareau MG, Ho NK, Brenner D, Sousa AJ, Lebourhis L, Mak TW, Girardin SE, Philpott DJ, Sherman PM. Enterohaemorrhagic, but not enteropathogenic, Escherichia coli infection of epithelial cells disrupts signalling responses to tumour necrosis factor-alpha. Microbiology. 2011 Oct;157(Pt 10):2963-73. doi: 10.1099/mic.0.051094-0. Epub 2011 Jul 28. PubMed PMID: 21798984.

Gareau MG, Wine E, Rodrigues DM, Cho JH, Whary MT, Philpott DJ, Macqueen G, Sherman PM. Bacterial infection causes stress-induced memory dysfunction in mice. Gut. 2011 Mar;60(3):307-17. doi: 10.1136/gut.2009.202515. Epub 2010 Oct 21.
PubMed PMID: 20966022.

Gareau MG, Sherman PM, Walker WA. Probiotics and the gut microbiota in intestinal health and disease. Nat Rev Gastroenterol Hepatol. 2010 Sep;7(9):503-14. doi: 10.1038/nrgastro.2010.117. Epub 2010 Jul 27. Review. PubMed PMID: 20664519; PubMed Central PMCID: PMC4748966.

Donato KA, Gareau MG, Wang YJ, Sherman PM. Lactobacillus rhamnosus GG attenuates interferon-{gamma} and tumour necrosis factor-alpha-induced barrier dysfunction and pro-inflammatory signalling. Microbiology. 2010 Nov;156(Pt 11):3288-97. doi: 10.1099/mic.0.040139-0. Epub 2010 Jul 23. PubMed PMID: 20656777.

Wine E, Shen-Tu G, Gareau MG, Goldberg HA, Licht C, Ngan BY, Sorensen ES, Greenaway J, Sodek J, Zohar R, Sherman PM. Osteopontin mediates Citrobacter rodentium-induced colonic epithelial cell hyperplasia and attaching-effacing lesions. Am J Pathol. 2010 Sep;177(3):1320-32. doi: 10.2353/ajpath.2010.091068. Epub 2010 Jul 22. PubMed PMID: 20651246; PubMed Central PMCID: PMC2928965.

Gareau MG, Wine E, Reardon C, Sherman PM. Probiotics prevent death caused by Citrobacter rodentium infection in neonatal mice. J Infect Dis. 2010 Jan 1;201(1):81-91. doi: 10.1086/648614. PubMed PMID: 19961304.

Wade PR, Palmer JM, Mabus J, Saunders PR, Prouty S, Chevalier K, Gareau MG McKenney S, Hornby PJ. Prokineticin-1 evokes secretory and contractile activity in rat small intestine. Neurogastroenterol Motil. 2010 May;22(5):e152-61. doi: 10.1111/j.1365-2982.2009.01426.x. Epub 2009 Nov 25. PubMed PMID: 19930539.

Wine E, Gareau MG, Johnson-Henry K, Sherman PM. Strain-specific probiotic (Lactobacillus helveticus) inhibition of Campylobacter jejuni invasion of human intestinal epithelial cells. FEMS Microbiol Lett. 2009 Nov;300(1):146-52. doi: 10.1111/j.1574-6968.2009.01781.x. Epub 2009 Sep 4. PubMed PMID: 19765084.

Teitelbaum AA, Gareau MG, Jury J, Yang PC, Perdue MH. Chronic peripheral administration of corticotropin-releasing factor causes colonic barrier dysfunction similar to psychological stress. Am J Physiol Gastrointest Liver Physiol. 2008 Sep;295(3):G452-9. doi: 10.1152/ajpgi.90210.2008. Epub 2008 Jul 17. PubMed PMID: 18635602.

Gareau MG, Silva MA, Perdue MH. Pathophysiological mechanisms of stress-induced intestinal damage. Curr Mol Med. 2008 Jun;8(4):274-81. Review. PubMed PMID: 18537635.

Gareau MG, Jury J, Perdue MH. Neonatal maternal separation of rat pups results in abnormal cholinergic regulation of epithelial permeability. Am J Physiol Gastrointest Liver Physiol. 2007 Jul;293(1):G198-203. Epub 2007 May 17. PubMed PMID: 17510196.

Gareau MG, Jury J, MacQueen G, Sherman PM, Perdue MH. Probiotic treatment of rat pups normalises corticosterone release and ameliorates colonic dysfunction induced by maternal separation. Gut. 2007 Nov;56(11):1522-8. Epub 2007 Mar 5. Erratum in: Gut. 2008 Apr;57(4):560. PubMed PMID: 17339238; PubMed Central PMCID: PMC2095679.

Gareau MG, Jury J, Yang PC, MacQueen G, Perdue MH. Neonatal maternal separation causes colonic dysfunction in rat pups including impaired host resistance. Pediatr Res. 2006 Jan;59(1):83-8. Epub 2005 Dec 2. PubMed PMID: 16326990.

Söderholm JD, Yates DA, Gareau MG, Yang PC, MacQueen G, Perdue MH. Neonatal maternal separation predisposes adult rats to colonic barrier dysfunction in response to mild stress. Am J Physiol Gastrointest Liver Physiol. 2002 Dec;283(6):G1257-63. Epub 2002 Aug 28. PubMed PMID: 12388189.